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ASP Isotopes inks deal to supply key isotope for potential cancer treatment options

2nd June 2025

By: Tasneem Bulbulia

Deputy Editor Online

     

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Isotope separation technologies company ASP Isotopes, which is a planning a secondary listing on the JSE later this year, and medical isotope production company Isotopia Molecular Imaging have entered into a strategic agreement to secure the supply of Gadolinium-160, a precursor isotope for producing terbium-161 (Tb-161), an emerging medical isotope in targeted radiotherapeutics.

Nasdaq-listed ASP has isotope enrichment facilities in Pretoria, South Africa.

The partnership between ASP and Isotopia is aimed at addressing supply challenges for Gd-160, enabling Isotopia to advance Tb-161-based therapies for prostate cancer, neuroendocrine tumours and other malignancies. 

Under the agreement, ASP will leverage its proprietary quantum enrichment technology to provide Isotopia with enriched Gd-160, a stable isotope required for the manufacture of Tb-161.

The collaboration aims to combine ASP’s work in large-scale isotope enrichment with Isotopia’s capabilities in commercial-scale medical isotope production.

“By supplying Gd-160, we are eliminating a major bottleneck in the development of Tb-161 therapies. Our investment in enrichment technology positions us to support the radiopharmaceutical industry's growing demand for stable isotopes.

“This partnership accelerates the path to clinical adoption of Tb-161, which could redefine cancer treatment paradigms,” says ASP CEO Paul Mann.

ASP last month also announced plans to acquire all shares in JSE-listed gas and energy company Renergen and create a strategic materials company with vertical and horizontal business integration.

The proposed merger is expected to combine ASP’s silicon-28 enrichment capabilities with Renergen's helium reserves to address critical supply vulnerabilities. Both companies supply the medical, nuclear and semiconductor industries.

Edited by Chanel de Bruyn
Creamer Media Senior Deputy Editor Online

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